Professional Info

Prof. CHAN, Hon Fai Vivas

(Assistant Professor)

Personal Information

Assistant Professor of the Institute for Tissue Engineering and Regenerative Medicine

Office: (852) 3943 3032
Address: Room 107A, 1/F, Lo Kwee-Seong Integrated Biomedical Science Building, Area 39, CUHK

Research Interests

1. Microfabrication approach for liver tissue engineering
2. Development of biomimetic biomaterial for tissue engineering and 3D microphysiological tissue model
3. Biomechanics of organ/tissue development

Selected Publications

1. Chan H.F., Ma S., Tian J., Leong K.W. (2017). High-throughput screening of microchip-synthesized genes in programmable double-emulsion droplets. Nanoscale 9 (10), 3485-3495

2. Chan H.F., Ma S., Leong K.W. (2016). Can microfluidics address biomanufacturing challenges in drug/gene/cell therapies? Regenerative Biomaterials 3(2):87-98

3. Chan H.F., Zhang Y., Leong K.W. (2016). Efficient One-Step Production of Microencapsulated Hepatocyte Spheroids with Enhanced Functions. Small 12(20):2720-30

4. Zhang J., Hu J., Chan H.F., Skibba M., Liang G., Chen M. (2016). iRGD decorated lipid-polymer hybrid nanoparticles for targeted co-delivery of doxorubicin and sorafenib to enhance anti-hepatocellular carcinoma efficacy. Nanomedicine, 12(5):1303-11

5. Jung Y., Ji H., Chen Z., Chan H.F., Atchison L., Klitzman B., Truskey G., Leong K.W. (2015). Scaffold-free, Human Mesenchymal Stem Cell-Based Tissue Engineered Blood Vessels. Sci Rep 12;5:15116

6. Hong S.*, Sycks D.*, Chan H.F.*, Lin S., Lopez G.P., Guilak F., Leong K.W., Zhao X. (2015). 3D Printing of Highly Stretchable and Tough Hydrogels into Complex, Cellularized Structures. Adv Mater 15;27(27):4035-40 (* These authors contributed equally)

7. Hong S., Jung Y., Yen R., Chan H.F., Leong K.W., Truskey G.A., Zhao X. (2014) Magnetoactive sponges for dynamic control of microfluidic flow patterns in microphysiological systems. Lab on a chip 14 (3), 514-521

8. Chiu Y.L., Chan H.F., Phua K.K., Zhang Y., Juul S., Knudsen B.R., Ho Y.P., Leong K.W. (2014). Synthesis of fluorosurfactants for emulsion-based biological applications. ACS Nano 22;8(4):3913-20

9. Cao C., Chan H.F., Zang J., Leong K.W., Zhao X. (2014). Harnessing localized ridges for high-aspect-ratio hierarchical patterns with dynamic tunability and multifunctionality. Adv Mater 19;26(11):1763-70

10. Truskey G.A., Achneck H.E., Bursac N., Chan H.F., Cheng C.S., Fernandez C., Hong S., Jung Y., Koves T., Kraus W.E., Leong K.W., Madden L., Reichert W.M., Zhao X. (2013) Design considerations for an integrated microphysiological muscle tissue for drug and tissue toxicity testing. Stem cell research & therapy 4 (1), S10

11. Chan H. F., Zhang Y., Ho Y., Chiu Y., Jung Y., Leong K.W. (2013) Rapid formation of multicellular spheroids in double-emulsion droplets with controllable microenvironment. Sci Rep 3:3462